In this case, all four families branch in similar manners because they are all of the same suborder, myomorpha. House mouse mus musculus longevity, ageing, and life history. They make ideal organisms for studies in many science fields such as genetics, biology, and medial research. The short genetic variations database dbsnp is a publicdomain archive for a broad collection of comman and rare small germline and somatic sequence variations. The confusion arises because of the gross morphological similarity of many mus species, many of which are only relatively distantly related and the phenotypic plasticity within the various species. In the book the genetics of the mouse published in 1943, grunberg wrote the taxonomy of the musculus group of mice is in urgent need of revision. Its geographic spread has been facilitated by its commensal relationship with humans which extends back at least 8,000 years. Pdf distribution, taxonomy, and conservation status of. The house mouse represents one group within this genus that is characterized by its ability to live in close association with people.
Pitt usda national wildlife research center, hawaii field station, hilo, hawaii abstract. Mus musculus castaneus waterhouse, 1843 subspecies. There are two parapatric taxa of commensal house mice of the mus musculus complex in europe. Dek dek protooncogene dna binding mus musculus house mouse.
They are the most commonly used mammalian research model and are used for research in genetics, psychology, medicine and other scientific disciplines. Mus musculus linnaeus, 1758 accepted name house mouse animalia chordata mammalia rodentia muridae mus mus musculus linnaeus, 1758. So at the end i would like to come up how similar they are. I would like to compare genome structure gene models annotation of mus musculus and mus spretus in terms of gene order, chromosome location etc. Natural environment which excludes labs, farms, zoos or anything that humans interfere with that is not natural. Mus musculus musculus ranges from c europe and scandinavia through e europe, ukraine, turkmenistan, sw georgia, nc iran, through n afghanistan north of the hindu kush and n asia to manchuria, korea, and japan prager et al. First molecular evidence of mus musculus bactrianus in. In the wild mice, as other rodents, are important food source for many predators. Dec 23, 2008 mus spretus diverged from mus musculus over one million years ago. House mouse colonization patterns on the subantarctic kerguelen archipelago suggest singular primary invasions and resilience against reinvasion. Top this article has been rated as topimportance on the project. Wolfgang musculus 14971563, german reformed theologian. Mus musculus subspecies progress in biological sciences.
Description this data object was automatically created by bioconductor core team. Despite differences in their size and appearance, mice share a distinct genetic similarity to humans, and their ability to reproduce and mature quickly make them efficient and economical candidate mammals for scientific study. Pdf subspecies differentiation of the house mouse mus musculus. The house mouse mus musculus is a small mammal of the order rodentia, characteristically having a pointed snout, large rounded ears, and a long and hairy tail. The blue color represents different families of rodents. How to correctly write about taxonomic nomenclature. Originating in asia, several species and subspecies of mice have evolved within the genus mus in the past million years 1820.
Nomenclature and overview of the mouse mus musculus. Easiest mammal to breed and maintain in laboratory conditions. Mus musculus mouse, ncbim37 assembly raw computes stage. Mus musculus linnaeus, 1758 souris commune, house mouse. Compare mus musculus and mus spretus genome structure annotation. Bgee provides annotations and experiment annotations, and processed expression values. For each family and genus except for orchidaceae a short morphological description is provided followed by notes on taxonomy, distribution, evolution, and ecology. Although the average person cannot distinguish a field mouse from a house mouse, taxonomists have gone in the opposite direction describing numerous types of house mouse species.
Taxonomy mus musculus castaneus southeastern asian. Genomic resources for wild populations of the house mouse. It is one of the most abundant species of the genus mus. Mus musculus mouse taxon 10090 go based gene sets for use. Pdf mice mus musculus genome responses to methotrexate. It consists of a complex of several separate lineages and nearly 3000 different strains of natural mutants, and transgenic and targeted mutant mice. The mouse genome was sequenced in 2002 and it was shown that almost every gene in the mouse genome had a human homolog. Jun 17, 2018 mus musculus is its binomial name from greek. Download fulltext pdf mice mus musculus genome responses to methotrexate mtx and some plant extracts article pdf available in life science journal 94. Mus musculus is the best known mouse species in the world. Neighbourjoining tree of the 28 cytochromeb sequences referred to mus. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks. Stable integration of transgenes encoding an engineered n.
Both the rat and man belong to the class of vertebrates, mammalia. Here we report the expansion of the genetic code of mus musculus with various unnatural amino acids including n. Mus musculus the house mouse of north america and europe is the most frequently used animal in biomedical research. Laboratory mice are usually of the species mus musculus. Mus musculus linnaeus, 1758 old web site least concern. Clues from morphology article pdf available in acta theriologica 482. There have been a number of sub species of mus musculus that have been described. Lk3 transgenic mice mus musculus linnaeus, 1758 mus sp. Evolutionary relationships were inferred using a neighbourjoining nj tree.
While being great research animals, the house mouse can also cause problems for humans. Classify by taxonomy, protein existence pe level 1 and 2 mouse cdnas mouse ests 4852146 4842036 3588947 aligned 255814 254896 200186 aligned. Searching for sequence patterns, aligning proteins and cdnas to the genome. This article is within the scope of wikiproject rodents, a collaborative effort to improve the coverage of rodents on wikipedia. The brown color represents the order rodentia in which the species mus musculus belongs. Mus musculus domesticus schwarz and schwarz, 1943 subspecies.
Silver 1995, drawing on detailed genetic analysis, lists 8 true species in the mus subgenus plus 4 morphologically and biochemically distinct mus musculus subspecies that together form an m. The taxonomy of the genus mus is still not entirely clear and the last 30 years have seen a continuing reduction in the number of species recognised and a rearrangement of the phylogenetic tree. Mus musculus house mouse the mouse is one of the most useful models for comparison to humans as it is also a mammal. If you look at the mouse and the human genome sequences they are organised in a remarkably similar way and with much homology. Sequence divergence of mus spretus and mus musculus across a. This makes them the perfect candidate as test subjects, allowing us to experiment without much constraint, which wouldnt be feasible with human subjects, given. We use natural populations of house mice mus musculusto study the genetics of adaptations 1517.
Archaeological and paleontological evidence shows that the. Mus musculus l is the polytypic species which encompasses all the subspecies and geographical or chromosomal races of the house mouse. For thousands of years, house mice have been commensal with and have been transported by humans throughout the world 3. The confusion arises because of the gross morphological similarity of many mus species, many of which are only relatively distantly related and the. Mus musculus, the house mouse tree of life web project. A brief history of the science of naming things featured. It represents a collection of annotation packages that can be. Animals that are members of the genus mus can be further classified according to their relationship to humankind. The house mouse mus musculus is the most successful and most widely distributed invasive mammal except for humans 1, cited in 2. The genus mus refers to a specific genus of muroid rodents, all typically called mice the adjective muroid comes from the word muroidea, which is a large superfamily of rodents, including mice, rats, voles, hamsters, gerbils, and many other relatives.
Mus musculus musculus eastern mus musculus domesticus western western european mouse mediterranean m. While every effort has been made to provide the most reliable and uptodate information available. However, it is not a legal authority for statutory or regulatory purposes. For starters, there is their obvious usefulness in laboratory settings.
Some laboratory mouse strains such as c57bl6 are domesticated from mus musculus domesticus. The house mouse mus musculus is a eurasian polytypic species believed to. Dek dek protooncogene dna binding mus musculus house. Distribution, taxonomy, and conservation status of the perote mouse peromyscus bullatus rodentia. Mus musculus academic dictionaries and encyclopedias. Mus musculus, the house mouse, is one of the most important species for scientific research. Most of these strains are being studied in educational and research settings throughout the world. Mice mus musculus are an important research tool for modeling human disease progression and development in the lab. Mus species mus musculus common name house mouse synonyms mus molossinus, mus nordmanni, mus musculus cinereomaculatus, mus bactrianus tantillus, mus musculus varius, mus molossinus yonakuni lifespan, ageing, and relevant traits imr 0. One or more of the features that are needed to show you the maps functionality are not available in the web browser that you are using. B this article has been rated as bclass on the projects quality scale.
In some cultures, mice were protected and worshipped. The classifying and organizing of all livingthings. Mus musculus mouse taxon 10090 go derived msigdb format gene sets for use with gsea these gene set collections are in the form of. Sep, 2016 wild populations of the house mouse mus musculus represent the raw genetic material for the classical inbred strains in biomedical research and are a major model system for evolutionary biology. Share about 85% of their genes with humans, making them relevant for studying human disease.
An mus musculus in uska species han rodentia nga ginhulagway ni linnaeus hadton 1758. Mus musculus linnaeus, 1758 india biodiversity portal. Authorship, types, synonyms, homonyms, common names, taxonomic positions and number of subtaxa of species mus musculus linnaeus, 1758. Currently, an organism idenitified as mouse will be found under the name mus sp. Most of the laboratory mice are hybrid subspieces of the mus musculus. The house mouse mus musculus is a particularly wellsuited model system to approach such questions, since it has a defined history of splits into subspecies and populations and since extensive genome information is available. It is also the species which has paid the largest tribute to modern science, since the historical laboratory strains the old inbreds stem from this species through the old tradition of fancy mice. Molenbeekroute pdf writer mus musculus taxonomy pdf editor 1 hillside road middlesex ub1 2pdfonline dispositif orseck pdf merge eb 420 pdf995 teoria monetaria moderna pdf file introduccion ala cartografia geologica pdf introduccion ala cartografia geologica pdf learning styles journal pdf algerie teoria monetaria moderna pdf file. Essa especie e membro da classe mammalia, ordem rodentia, familia muridae, genero mus, especie mus musculus. If it is important to see all records for mus musculus, you should therefore consider retrieving the records for mus sp. Every known species extinct or extant, whether animal, plant, bacteria, or mineral has a binomial name. Itis taxonomy is based on the latest scientific consensus available, and is provided as a general reference source for interested parties. The laboratory mouse is a small mammal of the order rodentia which is bred and used for scientific research. Animals in north america represent the subspecies musculus, castaneus and domesticus.
The house mouse is a commensal species native to eurasia that has been introduced nearly worldwide. Used in the discovery of antibiotics including penicillin, streptomycin, and in the development of vaccines for yellow fever and polio. Mus musculus the house mouse probably has a world distribution more extensive than any mammal, apart from humans. Andreas musculus 15141581, german lutheran theologian. Mus musculus domesticus, the western european house mouse, is a subspecies of the house mouse mus musculus. Mus musculus bactrianus southwestern asian house mouse, mus. Mus musculus linnaeus, 1758 occupies northern parts of eurasia, from northern and central europe to the. Species are easy to write about, even if almost every biologist has a different opinion on what a species actually is, and even if species from one part of the tree of life act totally different than species from another part. Two organisms are members of the same species if they meet all of the following criteria. The first mouse gene was isolated in 1977 and started a huge growth in mouse genetics. An mus musculus in nahilalakip ha genus nga mus, ngan familia nga muridae. Im reading through a number of articles that use partial hepatectomy in mus musculus to study the mechanisms for liver regeneration 1, 2, 3.
It has three tissue layers, an ectoderm which forms nervous tissue and other organs, a mesoderm which forms the reproductive structures and other parts, and an endoderm which builds the gut and other internal organs. These mice are genetically and phenotypically divergent. Other names, lk3 transgenic mice mus musculus linnaeus, 1758 mus sp. Ginklasipika han iucn an species komo diri gud kababarakan. However, the term mouse can also be applied to species outside of this genus. We use natural populations of house mice mus musculus to study the genetics of adaptations. Taxonomy or plant systematics, despite what people would have you believe, really is not an exacting science in many ways this statement mainly applies to the identification process, so. Sequence divergence of mus spretus and mus musculus across.
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